1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE

CAS NO.：3975-77-7
Empirical Formula: C18H29Br
Molecular Weight: 325.33
MDL number: MFCD00191861
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-18 17:23:41

What is 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE?

The Uses of 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE

1-Bromo-2,4,6-tri-tert-butylbenzene was used in the synthesis of bulky biarylphosphine ligand. This ligand was reported to participate in the Pd-catalyzed C-O cross-coupling of a wide range of aryl halides and phenols under milder conditions. It was used to investigate the effect on oligomerization of increased steric bulk in dimethylindium(III) chalcogenolates. It may be used to form α,α-dimethyl-β-phenyl hydrostyrene by reacting with phenylboronic acid.

General Description

1-Bromo-2,4,6-tri-tert-butylbenzene (2,4,6-tri-tert-butylbromobenzene) is a hindered aryl bromide. 1-Bromo-2,4,6-tri-tert-butylbenzene on reaction with phenylboronic acid yields α,α-dimethyl-β-phenyl hydrostyrene.

Properties of 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE

Melting point:	168-173 °C (lit.)
Boiling point:	299.7±9.0 °C(Predicted)
Density	1.064±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
BRN	1913257

Safety information for 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.