1-Bromo-2,3-epoxypropane

Synonym(s):1-Bromo-2,3-epoxypropane

CAS NO.：3132-64-7
Empirical Formula: C3H5BrO
Molecular Weight: 136.98
MDL number: MFCD00005130
EINECS: 221-525-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-30 21:22:42

What is 1-Bromo-2,3-epoxypropane?

Chemical properties

colourless liquid

The Uses of 1-Bromo-2,3-epoxypropane

Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies.

Definition

ChEBI: An epoxide that is oxirane substituted by a bromomethyl group at position 2.

General Description

A colorless volatile liquid. Flash point 22°F. Slightly soluble in water and denser than water. Toxic by inhalation and ingestion. A strong skin irritant. Used to make rubber.

Air & Water Reactions

Highly flammable. Slightly soluble in water. Sensitive to prolonged exposure to light and moisture.

Reactivity Profile

1-Bromo-2,3-epoxypropane reacts with acids, bases, oxidizing agents, Na, Zn, Al, Mg and their alloys. .

Health Hazard

TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Human mutation data reported. A dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Br-. See also BROMIDES.

Properties of 1-Bromo-2,3-epoxypropane

Melting point:	−40 °C(lit.)
Boiling point:	134-136 °C(lit.)
Density	1.67
refractive index	n20/D 1.482(lit.)
Flash point:	133 °F
storage temp.	2-8°C
solubility	Chloroform (Soluble), Methanol (Sparingly)
form	Oil
color	Colourless
Specific Gravity	1.668 (20/4℃)
BRN	79786
Stability:	Stable. Incompatible with acids, bases, oxidizing agents, many of the more active metals.
CAS DataBase Reference	3132-64-7(CAS DataBase Reference)
NIST Chemistry Reference	1-Bromo-2,3-epoxypropane(3132-64-7)
EPA Substance Registry System	Epibromohydrin (3132-64-7)

Safety information for 1-Bromo-2,3-epoxypropane

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H226:Flammable liquids H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention.