1-(4-Fluorophenyl)piperazine

CAS NO.：2252-63-3
Empirical Formula: C10H13FN2
Molecular Weight: 180.22
MDL number: MFCD00005960
EINECS: 218-846-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:24

What is 1-(4-Fluorophenyl)piperazine?

Chemical properties

clear yellowish liquid after melting

The Uses of 1-(4-Fluorophenyl)piperazine

1-(4-Fluorophenyl)piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidatio n.

The Uses of 1-(4-Fluorophenyl)piperazine

1-(4-Fluorophenyl)piperazine was used in the synthesis of N,N-disubstituted piperazine. It is a major metabolite of niaparazine, a sedative, a hypnotic drug.

Properties of 1-(4-Fluorophenyl)piperazine

Melting point:	30-33 °C (lit.)
Boiling point:	118-123 °C/0.1 mmHg (lit.)
Density	1.0
refractive index	1.5585-1.5605
Flash point:	>230 °F
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
pka	8.93±0.10(Predicted)
form	Liquid After Melting
color	Clear yellow
Water Solubility	Insoluble in water.
Sensitive	Air Sensitive
BRN	610723
CAS DataBase Reference	2252-63-3(CAS DataBase Reference)
NIST Chemistry Reference	1-(P-fluorophenyl)piperazine(2252-63-3)

Safety information for 1-(4-Fluorophenyl)piperazine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.