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HomeProduct name list(-)-PERILLYL ALCOHOL

(-)-PERILLYL ALCOHOL

Synonym(s):(S)-p-Mentha-1,8-dien-7-ol;(S)-4-Isopropenyl-1-cyclohexenylmethanol;p-Mentha-1,8-diene-7-ol

  • CAS NO.:18457-55-1
  • Empirical Formula: C10H16O
  • Molecular Weight: 152.23
  • MDL number: MFCD00062995
  • EINECS: 629-611-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-07 21:39:59
(-)-PERILLYL ALCOHOL Structural

What is (-)-PERILLYL ALCOHOL?

Description

(–)-Perillyl alcohol is a monoterpene alcohol that has been found in lavender essential oil and has diverse biological activities. It reduces production of hydroperoxidienes and thiobarbituric acid reactive substances (TBARS) in vitro in a concentration-dependent manner. (–)-Perillyl alcohol inhibits PANC-1 pancreatic carcinoma cell and H-Ras-transformed fibroblast growth when used at a concentration of 1 mM. It also inhibits the growth of P. aeruginosa, E. coli, S. aureus, and C. albicans (MICs = 480-2,900 ppm).

The Uses of (-)-PERILLYL ALCOHOL

(-)-Perillyl Alcohol is a monoterpene that induces apoptosis in colon tumor cells. Also, it is used in preparation of terpene-vanilloid conjugates as anti-inflammatory agents.

What are the applications of Application

(?)-Perillyl Alcohol is A monoterpene that induces apoptosis in colon tumor cells

Definition

ChEBI: (S)-(-)-perillyl alcohol is a perillyl alcohol in which the chiral centre has S configuration. It is an enantiomer of a (R)-(+)-perillyl alcohol.

General Description

(S)-(-)-Perillyl alcohol is a monoterpenoid compound found in the essential oils of cherries, lavender and spearmint. It shows potent anticancer activity.

Properties of (-)-PERILLYL ALCOHOL

Boiling point: 119-121 °C11 mm Hg(lit.)
alpha  -101o (NEAT)
Density  0.96 g/mL at 25 °C(lit.)
refractive index  n20/D 1.501
Flash point: >230 °F
storage temp.  2-8°C
solubility  Chloroform (Sparingly), Methanol (Sparingly)
form  neat
pka 14.85±0.10(Predicted)
form  Liquid
Specific Gravity 0.960
color  Colourless
optical activity [α]22/D 88°, c = 1 in methanol
BRN  2501605
CAS DataBase Reference 18457-55-1(CAS DataBase Reference)

Safety information for (-)-PERILLYL ALCOHOL

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (-)-PERILLYL ALCOHOL

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