(±)-Ibuprofen Methyl Ester

CAS NO.：61566-34-5
Empirical Formula: C14H20O2
Molecular Weight: 220.31
MDL number: MFCD00869922
EINECS: 262-853-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is (±)-Ibuprofen Methyl Ester?

The Uses of (±)-Ibuprofen Methyl Ester

(±)-Ibuprofen Methyl Ester is a phototoxic, photoproduct of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen is also used as an anti-inflammatory drug.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 4858, 1988 DOI: 10.1021/jo00255a037
Synthesis, p. 1044, 1986 DOI: 10.1055/s-1986-31868

Properties of (±)-Ibuprofen Methyl Ester

Boiling point:	100 °C
Density	0.976±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Oil
color	Colourless

Safety information for (±)-Ibuprofen Methyl Ester

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.