(-)-BICUCULLINE METHOBROMIDE
- CAS NO.:73604-30-5
- Empirical Formula: C21H20NO6.Br
- Molecular Weight: 462.29
- MDL number: MFCD00055149
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is (-)-BICUCULLINE METHOBROMIDE?
The Uses of (-)-BICUCULLINE METHOBROMIDE
(-)-Bicuculline methobromide is an N-methylated derivative of the GABAA?antagonist bicuculline.
What are the applications of Application
(?)-Bicuculline methobromide is an N-methylated derivative of the GABAA antagonist bicuculline
Biological Activity
Methobromide salt of (+)-bicuculline ([R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one ). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.
storage
Room temperature
Properties of (-)-BICUCULLINE METHOBROMIDE
storage temp. | 2-8°C |
solubility | aqueous base: unstable |
form | solid |
color | white |
Water Solubility | Soluble in water (50mM) |
Sensitive | Light Sensitive |
Safety information for (-)-BICUCULLINE METHOBROMIDE
Signal word | Warning |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Environment GHS09 |
GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H330:Acute toxicity,inhalation H400:Hazardous to the aquatic environment, acute hazard |
Precautionary Statement Codes |
P320:Specific treatment is urgent (see … on this label). P330:Rinse mouth. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up. |
Computed Descriptors for (-)-BICUCULLINE METHOBROMIDE
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Tubulysin G Tubulysin A Tubulysin M Tubulysin H Diethyl Aluminium Cyanide (1.0 M in Toluene) 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 3-N-BOC-(S)-AMINO BUTYRONITRILE 4,4-DIFLUOROPIPERIDINE CYCLOBUTYLAMINE HYDROCHLORIDE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2,2-Difluoropropanol Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell 2-Methyl-4- nitro Benzoic acid 3-fluoro-4- thiomorpholinoaniline Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
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