(-)-[3R,4S]-CHROMANOL 293B
- CAS NO.:163163-24-4
- Empirical Formula: C15H20N2O4S
- Molecular Weight: 324.4
- MDL number: MFCD06798368
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is (-)-[3R,4S]-CHROMANOL 293B?
What are the applications of Application
(?)-[3R,4S]-Chromanol 293B is a selective inhibitor of the slow component of delayed rectifier K+ current
Definition
ChEBI: Chromanol 293B is a 1-benzopyran.
Biological Activity
Enantiomer that selectively inhibits the slow component of delayed rectifier K + current (I Ks ). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC 50 values are 1.36 and 9.6 μ M respectively). Has negligible inhibitory action at hERG channels (IC 50 > 30 μ M).
storage
Room temperature
Properties of (-)-[3R,4S]-CHROMANOL 293B
Melting point: | 192 °C |
Boiling point: | 474.1±55.0 °C(Predicted) |
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | DMSO: 18 mg/mL |
form | solid |
pka | 12.96±0.60(Predicted) |
color | white |
Safety information for (-)-[3R,4S]-CHROMANOL 293B
Computed Descriptors for (-)-[3R,4S]-CHROMANOL 293B
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
2-(3-CYANO-PHENYL)ETHANOL
4-TERT-BUTOXYBENZONITRILE
(R)-3-(1-aminoethyl)benzonitrile
6-METHYL-CHROMAN-4-YLAMINE HYDROCHLORIDE
(-)-[3R,4S]-CHROMANOL 293B
CHROMANOL 293B
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