(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Synonym(s):(±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid
- CAS NO.:100828-16-8
- Empirical Formula: C8H17N2O5P
- Molecular Weight: 252.2
- MDL number: MFCD00055136
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID?
The Uses of (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity.
What are the applications of Application
(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity
Synthesis Reference(s)
Tetrahedron Letters, 30, p. 5193, 1989 DOI: 10.1016/S0040-4039(01)93739-6
Biological Activity
Potent NMDA antagonist. See separate isomer (3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid ).
Biochem/physiol Actions
Potent and selective NMDA glutamate receptor antagonist; anticonvulsant.
storage
Room temperature (desiccate)
Properties of (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Boiling point: | 546.7±60.0 °C(Predicted) |
Density | 1.408±0.06 g/cm3(Predicted) |
storage temp. | Desiccate at RT |
solubility | H2O: 99.2 mg/mL |
form | solid |
pka | 1.89±0.20(Predicted) |
color | white |
Water Solubility | Soluble to 100 mM in water |
Safety information for (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
azaleucine
(+/-)-3-(2-CARBOXY-PIPERAZIN-4-YL) PROPYL-1-PHOSPHONIC ACID-[PROPYL-1,2-3H]-
2-Piperazinecarboxaldehyde
PIPERAZINE-2-CARBOXYLIC ACID
2-Methylpiperazine
2,3-Diaminopropionic acid
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
3-Aminopropylphosphonic acid
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