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7681-54-1

7681-54-1 structural image
Product Name: INDOMETHACIN SODIUM
Formula: C19H15ClNNaO4
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COMPUTED DESCRIPTORS

Molecular Weight 379.8 g/mol
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 4
Exact Mass 379.0587299 g/mol
Monoisotopic Mass 379.0587299 g/mol
Topological Polar Surface Area 71.4 Ų
Heavy Atom Count 26
Formal Charge 0
Complexity 512
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Indomethacin Sodium is the sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction.

RELATED SUPPLIERS

Ralington Pharma

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All suppliers(2)