554-57-4
Product Name:
Methazolamide
Formula:
C5H8N4O3S2
Synonyms:
N-(4-Methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene) acetamide;5-Acetylimino-4-methyl-·2-1,3,4-thiadiazoline-2-sulfonamide;Methazolamide;N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide;N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide, Carbonic Anhydrase Inhibitor, Methazolamide, CAIX Inhibitor III
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | CRYSTALS FROM WATER |
|---|---|
| Melting Point | 213.5 °C |
| Solubility | >35.4 [ug/mL] (The mean of the results at pH 7.4) |
| LogP | 0.13 |
| LogS | -1.83 |
| Dissociation Constants | 7.30 |
| Kovats Retention Index | 2187 |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H351:Carcinogenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 236.3 g/mol |
|---|---|
| XLogP3 | 0.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 1 |
| Exact Mass | 236.00378248 g/mol |
| Monoisotopic Mass | 236.00378248 g/mol |
| Topological Polar Surface Area | 139 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 419 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Methazolamide is a member of thiadiazoles and a sulfonamide.