50-07-7
Product Name:
Mitomycin C
Formula:
C15H18N4O5
Synonyms:
Mitocin C, MMC;Mitomycin;Mitomycin C, Streptomyces caespitosus - CAS 50-07-7 - Calbiochem
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Mitomycin c appears as blue-violet crystals. Used as an anti-tumor antibiotic complex. (EPA, 1998) |
---|---|
Color/Form | BLUE-VIOLET CRYSTALS |
Boiling Point | 534 °C |
Melting Point | Above 680 °F (EPA, 1998) |
Solubility | Soluble (NTP, 1992) |
LogP | -0.4 |
Henry's Law Constant | LogP = -0.38; Henry's Law constant = 2.5X10-10 atm-cu m/mol |
Stability/Shelf Life | Commercially available mitomycin powder is stable for at least 4 years at room temperature. |
Dissociation Constants | 10.9 |
Collision Cross Section | 169.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
Chemical Classes | Other Uses -> Pharmaceuticals |
SAFETY INFORMATION
Signal word | Danger |
---|---|
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H300:Acute toxicity,oral H351:Carcinogenicity |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
Molecular Weight | 334.33 g/mol |
---|---|
XLogP3 | -0.4 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 4 |
Exact Mass | 334.12771969 g/mol |
Monoisotopic Mass | 334.12771969 g/mol |
Topological Polar Surface Area | 147 Ų |
Heavy Atom Count | 24 |
Formal Charge | 0 |
Complexity | 757 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 4 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Mitomycin c appears as blue-violet crystals. Used as an anti-tumor antibiotic complex. (EPA, 1998)