16960-16-0
Product Name:
Tetracosactide acetate
Formula:
C136H210N40O31S
Synonyms:
α1-24-Corticotropin acetate salt;Tetracosactide;Tetracosactide acetate salt;Tetracosactrin acetate salt
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Optical Rotation | Specific optical rotation: -88 +/- 2 deg at 22 °C/D (c = 0.511 in 1% acetic acid). UV max (0.1 NaOH): 283, 289 nm (epsilon 8550, 8810) /Cosyntropin hexacetate/ |
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COMPUTED DESCRIPTORS
| Molecular Weight | 2933.4 g/mol |
|---|---|
| XLogP3 | -7.9 |
| Hydrogen Bond Donor Count | 42 |
| Hydrogen Bond Acceptor Count | 41 |
| Rotatable Bond Count | 96 |
| Exact Mass | 2932.5839961 g/mol |
| Monoisotopic Mass | 2931.5806412 g/mol |
| Topological Polar Surface Area | 1180 Ų |
| Heavy Atom Count | 208 |
| Formal Charge | 0 |
| Complexity | 6500 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 22 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Cosyntropin is a synthetically-derived subunit of the endogenous peptide pituitary hormone adrenocorticotropic hormone (ACTH). Consisting of the first 24 amino acids from the amino terminal of ACTH, Cortrosyn is usually prepared for injection and intended for diagnostic and not therapeutic use. Similar to endogenous ACTH, this agent stimulates the adrenal secretion of specific adrenal steroids that can be measured in the plasma. (NCI04)