CHEMICAL AND PHYSICAL PROPERTIES
| Other Experimental Properties | 33 amino acid glucagon-like peptide-2 ... analog manufactured using a strain of Escherichia coli modified by recombinant DNA technology |
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COMPUTED DESCRIPTORS
| Molecular Weight | 3752.1 g/mol |
|---|---|
| XLogP3 | -15.2 |
| Hydrogen Bond Donor Count | 55 |
| Hydrogen Bond Acceptor Count | 60 |
| Rotatable Bond Count | 126 |
| Exact Mass | 3750.8028943 g/mol |
| Monoisotopic Mass | 3749.7995395 g/mol |
| Topological Polar Surface Area | 1650 Ų |
| Heavy Atom Count | 264 |
| Formal Charge | 0 |
| Complexity | 9030 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 38 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Teduglutide is a 33-membered polypeptide consisting of His, Gly, Asp, Gly, Ser, Phe, Ser, Asp, Glu, Met, Asn, Thr, Ile, Leu, Asp, Asn, Leu, Ala, Ala, Arg, Asp, Phe, Ile, Asn, Trp, Leu, Ile, Gln, Thr, Lys, Ile, Thr and Asp residues joined in sequence. A glucagon-like peptide-2 receptor agonist used for the treatment of short-bowel syndrome. It has a role as a glucagon-like peptide-2 receptor agonist, a metabolite, an antioxidant and a protective agent.