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132-73-0

132-73-0 structural image
Product Name: Chloroquine sulfate
Formula: C18H28ClN3O4S
Synonyms: Chloroquine sulfate monohydrate
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COMPUTED DESCRIPTORS

Molecular Weight 418.0 g/mol
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 8
Exact Mass 417.1489053 g/mol
Monoisotopic Mass 417.1489053 g/mol
Topological Polar Surface Area 111 Ų
Heavy Atom Count 27
Formal Charge 0
Complexity 390
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Chloroquine Sulfate is the sulfate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids.

RELATED SUPPLIERS

Triveni Interchem Private Limited

1Y
product:132-73-0 Chloroquine sulfate 98%
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