4-ethylmorpholine SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 4-ethylmorpholine
- CAS： 100-74-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 3
Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Skin corrosion, Sub-category 1B
Serious eye damage, Category 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H226 Flammable liquid and vapour
H302+H312 Harmful if swallowed or in contact with skin
H314 Causes severe skin burns and eye damage
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 4-ethylmorpholine
- Common names and synonyms: 4-ethylmorpholine
- CAS number: 100-74-3
- EC number: 202-885-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink.
Most important symptoms/effects, acute and delayed
Exposure can cause irritation of eyes, nose and throat. Contact with eyes may result in foggy vision and seeing halos around lights. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Absorbed through unbroken skin.
SECTION 5: Firefighting measures
Suitable extinguishing media
Alcohol foam, foam, carbon dioxide, dry chemical.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as ammonia, nitrogen oxides, and carbon monoxide, may be formed when involved in fire. Behavior in Fire: Can react vigorously with heat or flame. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, alcohol-resistant foam. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
1) remove all ignition sources. 2) ventilate area of spill or leak. 3) for small quantities, absorb on paper towels. evaporate in safe place (such as a fume hood). allow sufficient time for evaporating vapors to completely clear hood ductwork. burn paper in suitable location away from combustible materials.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. NO contact with hot surfaces. Above 32°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants.Store in a detached storehouse without any ignition source.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 5 ppm as TWA; (skin)
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Clear, low-colour.
-
Odour：
AMMONIACAL ODOR
-
Melting point/freezing point：
-68.4 °C. Remarks:Mean of duplicate measurements.
-
Boiling point or initial boiling point and boiling range：
138.6 °C. Atm. press.:1 013 hPa.
-
Flammability：
Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
27.5 °C. Atm. press.:100.5 kPa.
-
Auto-ignition temperature：
158 °C. Atm. press.:102.1 kPa. Remarks:No cool flames were observed. Ignition produced an orange flame.
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
kinematic viscosity (in mm2/s) = 1.176. Temperature:20°C. Remarks:Mean of 2 runs.;kinematic viscosity (in mm2/s) = 0.887. Temperature:40°C. Remarks:Mean of 2 runs.
-
Solubility：
greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Pow = 0.08. Temperature:24.6 °C.
-
Vapour pressure：
1.12 hPa. Temperature:25 °C.
-
Density and/or relative density：
0.9 g/cm3. Temperature:20 °C.
-
Relative vapour density：
4 (NTP, 1992) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic gases and vapours (ammonia, nitrogen oxides, carbon monoxide). Reacts violently with strong oxidants. This generates fire and explosion hazard. Attacks plastics, rubber and coatings.
Chemical stability
no data available
Possibility of hazardous reactions
A DANGEROUS FIRE HAZARD...N-ETHYL MORPHOLINE can react vigorously with oxidizing materials. It dissolves LiAlH4. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Can react vigorously with oxidizing materials.
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male) - > 1 500 - < 2 000 mg/kg bw.
- Inhalation: no data available
- Dermal: LD50 - rabbit (male/female) - 1 980.4 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the eyes. This may result in distortion of vision.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Leuciscus idus - 277 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 804 mg/L - 48 h.
- Toxicity to algae: EC10 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 61.2 mg/L - 96 h.
- Toxicity to microorganisms: EC20 - activated sludge, industrial - > 600 mg/L - 30 min. Remarks:Respiration rate.
Persistence and degradability
no data available
Bioaccumulative potential
Because it is miscible in water(2), bioconcentration in aquatic organisms is not expected to be an important fate process for N-ethylmorpholine(1,SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indexes(1), the Koc for N-ethylmorpholine can be estimated to be about 12(SRC). According to a suggested classification scheme(2), this estimated Koc value suggests that N-ethylmorpholine has very high soil mobility(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2734 (For reference only, please check.)
IMDG: UN2734 (For reference only, please check.)
IATA: UN2734 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: AMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S. or POLYAMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S. (For reference only, please check.)
IMDG: AMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S. or POLYAMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S. (For reference only, please check.)
IATA: AMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S. or POLYAMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 8 (For reference only, please check.)
IMDG: 8 (For reference only, please check.)
IATA: 8 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
MAK value not established but full documentation is available (MAK IIb).