Acute toxicity - Category 4, Oral
Skin sensitization, Category 1
Specific target organ toxicity – repeated exposure, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H373 May cause damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
no data available
Fresh air, rest. Seek medical attention if you feel unwell.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . See Notes.
no data available
Airway protection. Ensure that a clear airway exists. Intubate the patient and aspirate the secretions with a large-bore suction device if necessary. Administer oxygen by mechanically assisted pulmonary ventilation if respiration is depressed. Improve tissue oxygenation as much as possible before administering atropine, to minimize the risk of ventricular fibrillation. In severe poisonings, it may be necessary to support pulmonary ventilation mechanically for several days. N-methyl carbamate insecticides
Fire Extinguishing Media: Water, foam, dry powder, CO2.
Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion if formulations contain flammable/explosive solvents.
Use water spray, foam, powder, carbon dioxide.
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
If a spill occurs, clean it up promptly. Don't wash it away. Instead, sprinkle the spill with sawdust, vermiculite, or kitty litter. Sweep it into a plastic garbage bag, and dispose of it as directed on the pesticide product label./Residential users/
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Store in original container in locked storage area. Prevent Tick Collar for Dogs
no data available
no data available
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Wear safety spectacles or face shield.
Protective gloves. Protective clothing.
Use ventilation (not if powder).
no data available
Amitraz is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic mange in dogs.
White/pale yellow crystalline solid
Slight amine odor
86-87°C
450.7°C at 760mmHg
Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
no data available
no data available
no data available
no data available
no data available
no data available
Soluble in most organic solvents.
log Kow = 5.50
2.0X10-6 mm Hg at 25 deg C
0.98g/cm3
no data available
no data available
Decomposes on burning. This produces toxic fumes including nitrogen oxides.
Amitraz is unstable under acidic conditions.
Unstable in acid.
no data available
Amitraz is unstable under acidic conditions.
When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
no data available
no data available
no data available
no data available
Cancer Classification: Group C Possible Human Carcinogen
no data available
The substance may cause effects on the central nervous system and cardiovascular system.
no data available
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached.
AEROBIC: Amitraz degrades in aerobic soil with a half-life of less than one day. N-(2,4-dimethylphenyl)-N'-methylmethanimidamide (BTS27271)(2) and 2,4-dimethylphenylformamide (NTS27919)(2), formed via hydrolysuis at the C-N [N-methylmethanimidaminde] bond, are the primary metabolites of amitraz.(1).
Measured BCF values of 588-1,838 in bluegill sunfish have been reported for amitraz(1). According to a classification scheme(2), these BCF values suggest bioconcentration in aquatic organisms is high to very high(SRC), provided the compound is not metabolized by the organism(SRC).
The Koc of amitraz was reported to range from 1,000(1) to 2000(2). According to a classification scheme(3), this Koc value indicates amitraz will have low mobility in soil. Although it is considered to be moderately mobile in some soils (batch equilibrium studies indicated moderate mobility in sandy loam, silt loam and clay soils and very mobile in clay soils), amitraz degrades rapidly and therefore is not considered to be a serious concern for groundwater contamination(4). Amitraz had measured Freundlich adsorption coefficients of 1.69 in a Shelby sandy soil, 3.01 in a Spencer sand, 89.13 in a Terling clay and 16.31 in a Shelford clay(4). The pKa of amitraz is 4.20(2), indicating that this compound will partially exist in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).
no data available
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
ADR/RID: Yes
IMDG: Yes
IATA: Yes
no data available
no data available
If the pesticide is present under the form of a formulation containing hydrocarbon solvents, vomiting may not be induced.Carrier solvents used in commercial formulations may change physical and toxicological properties.If the substance is formulated with solvents also consult the ICSCs of these materials.