API Sofosbuvir CAS 1190307-88-0/Intermediate of Sofosbuvir
| Price | USD40.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:10 tons
- Time:2021-08-13
Product Details
- Product NameSofosbuvir
- CAS No.1190307-88-0
- EINECS No.695-717-4
- MFC22H29FN3O9P
- MW529.45
- AppearanceSolidWhite
- density 1.41
- storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
- Melting point 122-124°C
Product Name: Sofosbuvir
Synonyms: GS-7977;N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;PSI 7977;sofosbuvir;GS-7977/sofosbuvir;sofosbuvir, PSI7977;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-Methyltetrahydrofuran-2-yl)Methoxy)(phenoxy)phosphoryl)aMino)propanoate;PSI-7977 Discontinued
Molecular Formula: C22H29FN3O9P
Molecular Weight: 529.4525242
CAS No.: 1190307-88-0
Appearance: white crystalline powder
Puity: 99.0% up by HPLC
Usage: treat for chronic hepatitis C
sofosbuvir is first without joint interferon can be safe and effective drug for the treatment of certain types of hepatitis c.Clinical trials confirm for type 1 and 4 c, the drug combination of polyethylene glycol (peg) interferon and ribavirin overall sustained virological response (SVR) is as high as 90%;In view of the type 2 c, the drug plus ribavirin SVR is 89% - 95%;In view of the 3 c, the drug plus ribavirin SVR is 61% - 63%.
Function
sofosbuvir is a kind of hepatitis c virus (HCV) NS5B polymerase inhibitors nucleotide analogues, applicable to as united antiviral treatment composition in the treatment of chronic hepatitis c (CHC) infection.
sofosbuvir confirmed by test can effectively treat genotype 1, 2, 3, or 4 c subjects, including within milan criteria are awaiting liver transplantation of HCC subjects and co-infection of HCV/HIV - 1 subjects.
Company Profile Introduction
Shijiazhuang Tongyang Import and Export Co., LTD , located in Shijiazhuang City,which is the capital of Hebei Province and hub sector among Beijing, Tianjin, and Hebei.We have the advantage of convenient transportation.Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.In recent five years, the company has implemented the strategy of "going out" vigorously.We has established our branches in Hubei China, Vietnam and Mexico, making our market and sales network more and more perfect.Our company will continue to adhere to the strategic positioning of fine chemical industry in the future and competition ideas of irreplaceable product differentiation,and strive to become to the leading of Chinese chemical industry.Shijiazhuang Tongyang Import and Export Co., LTD , located in Shijiazhuang City,which is the capital of Hebei Province and hub sector among Beijing, Tianjin, and Hebei.We have the advantage of convenient transportation.Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.In recent five years, the company has implemented the strategy of "going out" vigorously.We has established our branches in Hubei China, Vietnam and Mexico, making our market and sales network more and more perfect.Our company will continue to adhere to the strategic positioning of fine chemical industry in the future and competition ideas of irreplaceable product differentiation,and strive to become to the leading of Chinese chemical industry.
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- Since:2015-05-06
- Address: room 1916,haiyuetiandi,66 yuehua west road,xiaoxi district