Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecompany AZD3759 ,1626387-80-1
AZD3759
AZD3759
AZD3759

AZD3759 ,1626387-80-1

Price USD50.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:20ton
  • Time:2021-08-07

Product Details

  • Product NameAZD3759
  • CAS No.1626387-80-1
  • EINECS No.1592732-453-0
  • MFC22H23ClFN5O3
  • MW459.9
  • AppearancesolidWhite to off-white
  • Boiling point 571.4±50.0 °C(Predicted)
  • density 1.358±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C

Contact us :

Whatsapp:+86 156 3213 8192

Wickr pro:1174573833@qq.com

Wickr:kmbktaylor

Email:aric258@163.com

 


new bmk/cas 5413-05-8
bmk cas 16648-44-5
Pmk cas 13605-48-6

new pmk cas 28578-16-7

MK2866  841205-47-8

S4 401900-40-1

S23 1010396-29-8

LGD-4033  1165910-22-4

MK677 159752-10-0

SR9009 1379686-30-2

SR9011 1379686-29-9

ACP-105 899821-23-9

YK-11 1370003-76-1

GW-0742 317318-84-6

RAD-140 118237-47-0

GW-501516 317318-70-0

N,N-dimethyl-2-phenylethylamine hydrochloride (USAF EL-79) 10275-21-5


cas 1451-82-7
cas 49851-31-2
BDO cas 110-63-4
Tetracaine hcl cas 136-47-0
Procaine cas 59-46-1
Lidocaine cas 137-58-6
Benzocaine cas 94-09-7


Product Name:AZD 3759
Synonyms:AZD 3759;AZD3759;AZD-3759;(2R)-2,4-Dimethyl-1-piperazinecarboxylic acid 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester;HY-18750;azd3579;1-Piperazinecarboxylic acid, 2,4-dimethyl-, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester, (2R)-;1-PIPERAZINECARBOXYLIC ACID, 2,4-DIMETHYL-, 4-[(3-CHLORO-2-FLUOROPHENYL)AMINO]-7-METHOXY-6-QUINAZOLINYL ESTER
CAS:1626387-80-1
MF:C22H23ClFN5O3
MW:459.9
EINECS:1592732-453-0
Product Categories:API
Mol File:1626387-80-1.mol
AZD 3759 Structure
AZD 3759 Chemical PropertiesBoiling point 571.4±50.0 °C(Predicted)density 1.358±0.06 g/cm3(Predicted)pka6.71±0.40(Predicted)
Safety Information
MSDS Information                            
AZD 3759 Usage And SynthesisSelective EGFR inhibitor

AZD3759 is a selective EGFR inhibitor that can fully penetrate the blood-brain barrier (BBB), with equal free concentrations in the blood, cerebrospinal fluid, and brain tissue. Treatment with AZD3759 causes tumor regression in subcutaneous xenograft, leptomeningeal metastasis (LM), and brain metastasis (BM) lung cancer models and prevents the development of BM in nude mice.

DescriptionAZD3759 is an EGFP inhibitor (Epidermal growth factor receptor tyrosine kinase inhibitor) with blood brain barrier (BBB) penetration. It has the potential for the treatment of non-small cell lung cancer (NSCLC), with brain metastases (BM) and leptomengingeal metastases (LM) since this type of cancer often contain a lot of activating mutations of the epidermal growth factor receptor (EGFR). It has excellent capability of penetrating the blood brain barrier to reach the central nervous system



NMN  cas 1094-61-7
NR   cas 1341-23-7
Boric acid cas 11113-50-1
N-Isopropylbenzylamine cas 102-97-6

Tetramisole hcl cas 5086-74-8
Levamisole cas 14769-73-4
Phenacetin cas 62-44-2
2-iodo-1-p-tolyl-propan-1-one cas 236117-38-7


Paracetamol cas 103-90-2
Pregabalin cas 148553-50-8
Xylazine cas 7361-61-7
(2-Bromoethyl)benzene cas 103-63-9


4'-Methylpropiophenone 

cas 5337-93-9
Valerophenone cas 100

Company Profile Introduction

Shijiazhuang Tongyang Import and Export Co., LTD , located in Shijiazhuang City,which is the capital of Hebei Province and hub sector among Beijing, Tianjin, and Hebei.We have the advantage of convenient transportation.Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.In recent five years, the company has implemented the strategy of "going out" vigorously.We has established our branches in Hubei China, Vietnam and Mexico, making our market and sales network more and more perfect.Our company will continue to adhere to the strategic positioning of fine chemical industry in the future and competition ideas of irreplaceable product differentiation,and strive to become to the leading of Chinese chemical industry.Shijiazhuang Tongyang Import and Export Co., LTD , located in Shijiazhuang City,which is the capital of Hebei Province and hub sector among Beijing, Tianjin, and Hebei.We have the advantage of convenient transportation.Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.In recent five years, the company has implemented the strategy of "going out" vigorously.We has established our branches in Hubei China, Vietnam and Mexico, making our market and sales network more and more perfect.Our company will continue to adhere to the strategic positioning of fine chemical industry in the future and competition ideas of irreplaceable product differentiation,and strive to become to the leading of Chinese chemical industry.

  • Since:2015-05-06
  • Address: room 1916,haiyuetiandi,66 yuehua west road,xiaoxi district
INQUIRY