ZYMOSAN A
Synonym(s):Yeast Cell Wall
- CAS NO.:58856-93-2
- Empirical Formula: n.a.
- Molecular Weight: 0
- MDL number: MFCD00082157
- EINECS: 232-725-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-11 19:18:13
What is ZYMOSAN A?
The Uses of ZYMOSAN A
Zymosan A from Saccharomyces cerevisiae has been used:
- as a positive control to determine the activation of complement cascade
- for respiratory burst (RB) assay
- to assess its effects on performance, immunity, heat shock protein and apoptosis related gene expressions of dairy cows under heat stress (HS)
- a stimulating agent in Krebs-Ringer phosphate (KRP) medium
- to induce thermal hyperalgesia in mice
What are the applications of Application
Zymosan A from Saccharomyces cerevisiae is prepared from yeast cell wall and consists of protein-carbohydrate complexes
Biochem/physiol Actions
Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages, zymosan-induced responses include the induction of proinflammatory cytokines, arachidonate mobilization, protein phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels suggesting a role for the latter in macrophage activation besides proliferation. It potentiates acute liver damage after galactosamine injection suggesting that certain types of nonparenchymal cells other than Kupffer cells are involved in zymosan action. Zymosan A, a 13 beta glucan contributes to the development of organic dust-induced respiratory disease.
Properties of ZYMOSAN A
RTECS | ZI2750000 |
storage temp. | 2-8°C |
solubility | Chloroform: 100 μg/ml; DMSO: 200 μg/ml; Ethanol: 100 μg/ml |
form | Powder |
color | off-white to light brown |
Safety information for ZYMOSAN A
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for ZYMOSAN A
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