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HomeProduct name listZYMOSAN A

ZYMOSAN A

Synonym(s):Yeast Cell Wall

  • CAS NO.:58856-93-2
  • Empirical Formula: n.a.
  • Molecular Weight: 0
  • MDL number: MFCD00082157
  • EINECS: 232-725-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-06-11 19:18:13

What is ZYMOSAN A?

The Uses of ZYMOSAN A

Zymosan A from Saccharomyces cerevisiae has been used:

  • as a positive control to determine the activation of complement cascade
  • for respiratory burst (RB) assay
  • to assess its effects on performance, immunity, heat shock protein and apoptosis related gene expressions of dairy cows under heat stress (HS)
  • a stimulating agent in Krebs-Ringer phosphate (KRP) medium
  • to induce thermal hyperalgesia in mice

What are the applications of Application

Zymosan A from Saccharomyces cerevisiae is prepared from yeast cell wall and consists of protein-carbohydrate complexes

Biochem/physiol Actions

Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages, zymosan-induced responses include the induction of proinflammatory cytokines, arachidonate mobilization, protein phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels suggesting a role for the latter in macrophage activation besides proliferation. It potentiates acute liver damage after galactosamine injection suggesting that certain types of nonparenchymal cells other than Kupffer cells are involved in zymosan action. Zymosan A, a 13 beta glucan contributes to the development of organic dust-induced respiratory disease.

Properties of ZYMOSAN A

RTECS  ZI2750000
storage temp.  2-8°C
solubility  Chloroform: 100 μg/ml; DMSO: 200 μg/ml; Ethanol: 100 μg/ml
form  Powder
color  off-white to light brown

Safety information for ZYMOSAN A

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for ZYMOSAN A

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