ZOPICLONE N-OXIDE

Synonym(s):(5RS)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate 4-oxide;Zopiclone oxide

CAS NO.：43200-96-0
Empirical Formula: C17H17ClN6O4
Molecular Weight: 404.81
MDL number: MFCD00871938
EINECS: 641-896-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-18 11:31:15

What is ZOPICLONE N-OXIDE?

Chemical properties

Off-White to Pale Beige Solid

The Uses of ZOPICLONE N-OXIDE

A metabolite of Zopiclone

The Uses of ZOPICLONE N-OXIDE

Eszopiclone impurity A.

General Description

Zopiclone N-oxide is a primary, active metabolite of zopiclone in urine as well as a major pharmaceutical impurity of zopiclone known as eszopiclone impurity A. The parent drug, zopiclone, is a non-benzodiazepine hypnotic sold under the trade names Imovane^?and ZImovane^?and is used in the treatment of insomnia.

Properties of ZOPICLONE N-OXIDE

Melting point:	>140°C (dec.)
Flash point:	9℃
storage temp.	2-8°C
solubility	Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Soni
pka	4.92±0.20(Predicted)
form	neat
color	White to Light Brown

Safety information for ZOPICLONE N-OXIDE

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.