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HomeProduct name listZOPICLONE N-OXIDE

ZOPICLONE N-OXIDE

Synonym(s):(5RS)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate 4-oxide;Zopiclone oxide

  • CAS NO.:43200-96-0
  • Empirical Formula: C17H17ClN6O4
  • Molecular Weight: 404.81
  • MDL number: MFCD00871938
  • EINECS: 641-896-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-18 11:31:15
ZOPICLONE N-OXIDE Structural

What is ZOPICLONE N-OXIDE?

Chemical properties

Off-White to Pale Beige Solid

The Uses of ZOPICLONE N-OXIDE

A metabolite of Zopiclone

The Uses of ZOPICLONE N-OXIDE

Eszopiclone impurity A.

General Description

Zopiclone N-oxide is a primary, active metabolite of zopiclone in urine as well as a major pharmaceutical impurity of zopiclone known as eszopiclone impurity A. The parent drug, zopiclone, is a non-benzodiazepine hypnotic sold under the trade names Imovane?and ZImovane?and is used in the treatment of insomnia.

Properties of ZOPICLONE N-OXIDE

Melting point: >140°C (dec.)
Flash point: 9℃
storage temp.  2-8°C
solubility  Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Soni
pka 4.92±0.20(Predicted)
form  neat
color  White to Light Brown

Safety information for ZOPICLONE N-OXIDE

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Computed Descriptors for ZOPICLONE N-OXIDE

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