ZK164015
- CAS NO.:177583-70-9
- Empirical Formula: C30H43NO4S
- Molecular Weight: 513.73
- MDL number: MFCD06798325
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is ZK164015?
The Uses of ZK164015
ZK 164015 is a potent ER silent antagonist.
What are the applications of Application
ZK 164015 is a potent ER silent antagonist
Definition
ChEBI: 2-(4-hydroxyphenyl)-3-methyl-1-(10-pentylsulfonyldecyl)-5-indolol is a phenylindole.
Biological Activity
Potent estrogen receptor silent antagonist. Inhibits 17b-estradiol stimulation of luciferase activity (IC 50 = 0.025 mM) and potently inhibits the growth of estrogen-sensitive human MCF-7 breast cancer cells in vitro (IC 50 ~ 1 nM).
Properties of ZK164015
Boiling point: | 712.4±55.0 °C(Predicted) |
Density | 1.13±0.1 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | Soluble to 25 mM in ethanol and to 100 mM in DMSO |
form | Powder |
pka | 10.17±0.15(Predicted) |
Safety information for ZK164015
Computed Descriptors for ZK164015
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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FUDAEUIGIJZUAY-UMIRZPQISA-N
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