ZK164015
- CAS NO.:177583-70-9
- Empirical Formula: C30H43NO4S
- Molecular Weight: 513.73
- MDL number: MFCD06798325
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is ZK164015?
The Uses of ZK164015
ZK 164015 is a potent ER silent antagonist.
What are the applications of Application
ZK 164015 is a potent ER silent antagonist
Definition
ChEBI: 2-(4-hydroxyphenyl)-3-methyl-1-(10-pentylsulfonyldecyl)-5-indolol is a phenylindole.
Biological Activity
Potent estrogen receptor silent antagonist. Inhibits 17b-estradiol stimulation of luciferase activity (IC 50 = 0.025 mM) and potently inhibits the growth of estrogen-sensitive human MCF-7 breast cancer cells in vitro (IC 50 ~ 1 nM).
Properties of ZK164015
Boiling point: | 712.4±55.0 °C(Predicted) |
Density | 1.13±0.1 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | Soluble to 25 mM in ethanol and to 100 mM in DMSO |
form | Powder |
pka | 10.17±0.15(Predicted) |
Safety information for ZK164015
Computed Descriptors for ZK164015
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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