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ZK164015

ZK164015 Structural

What is ZK164015?

The Uses of ZK164015

ZK 164015 is a potent ER silent antagonist.

What are the applications of Application

ZK 164015 is a potent ER silent antagonist

Definition

ChEBI: 2-(4-hydroxyphenyl)-3-methyl-1-(10-pentylsulfonyldecyl)-5-indolol is a phenylindole.

Biological Activity

Potent estrogen receptor silent antagonist. Inhibits 17b-estradiol stimulation of luciferase activity (IC 50 = 0.025 mM) and potently inhibits the growth of estrogen-sensitive human MCF-7 breast cancer cells in vitro (IC 50 ~ 1 nM).

Properties of ZK164015

Boiling point: 712.4±55.0 °C(Predicted)
Density  1.13±0.1 g/cm3(Predicted)
storage temp.  Store at RT
solubility  Soluble to 25 mM in ethanol and to 100 mM in DMSO
form  Powder
pka 10.17±0.15(Predicted)

Safety information for ZK164015

Computed Descriptors for ZK164015

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