(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

CAS NO.：1987887-92-2
Empirical Formula: C24H21N3O3
Molecular Weight: 399.44
Update Date: 2023-04-23 13:52:06

What is (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate?

The Uses of (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Properties of (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Melting point:	273 - 276°C
Boiling point:	641.3±55.0 °C(Predicted)
Density	1.316±0.06 g/cm3(Predicted)
storage temp.	Refrigerator, under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	11.16±0.20(Predicted)
color	Yellow to Orange

Safety information for (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Computed Descriptors for (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

New Products

6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Ivermectin EP Impurity B Rimegepant Impurity 3 Fosfomycin EP impurity D Tubulysin F (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin A Diethyl Aluminium Cyanide (1.0 M in Toluene) (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 1-(4-Fluorophenyl)piperidin-2-one Methyl 4-amino-3-(4-phenylpiperazin-1-yl)benzoate Methyl 4-amino-3-(dihexylamino)benzoate 3-Morpholino-1-[4-(2-oxo-1-piperidyl)phenyl]-5,6-dihydropyridin-2(1H)-one 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 5-Bromo-4,6-difluoro-2,3-dihydro-1h-indole 3-HYDROXY-8-FLUORONAPHTHALENE-1-BORONIC ACID PINACOL ESTER ((E)-3-(Dimethylamino)-2-methylacrylaldehyde

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