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HomeProduct name listWAY-151932

WAY-151932

  • CAS NO.:220460-92-4
  • Empirical Formula: C23H19ClN4O
  • Molecular Weight: 402.88
  • MDL number: MFCD05662330
  • Update Date: 2024-10-28 23:16:16
WAY-151932 Structural

What is WAY-151932?

Biological Activity

WAY-151932 is an antidiuretic hormone V2 receptor agonist with IC50 of 80.3 and 778 nM in human V2 and V1a binding assays, respectively.

in vitro

WAY-151932 (VNA-932) stimulates cAMP formation in LV2 cells expressing the hV 2 receptors in a dose-dependent manner with an EC 50 of 0.74±0.07 nM.

in vivo

Oral administration of WAY-151932 (VNA-932) to water-loaded conscious rats produces a dose-dependent decrease in urine volume (ED 50 =0.14 mg/kg, 2.5% starch in water vehicle) and a corresponding increase in osmolality without altering the urine electrolyte excretion profile.

Properties of WAY-151932

Boiling point: 630.6±55.0 °C(Predicted)
Density  1.33±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Soluble in DMSO
form  Solid
pka 0.04±0.12(Predicted)
color  White to off-white

Safety information for WAY-151932

Computed Descriptors for WAY-151932

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