Vilazodone-d8
- CAS NO.:1794789-93-7
- Empirical Formula: C26H26N5O2
- Molecular Weight: 440.51694
- MDL number: MFCD28900708
- Update Date: 2024-10-28 16:48:35
What is Vilazodone-d8?
Description
Vilazodone-d8 is intended for use as an internal standard for the quantification of vilazodone by GC- or LC-MS. Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively). It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg, respectively. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.
Chemical properties
Off-White to Pale Yellow Solid
The Uses of Vilazodone-d8
(Vilazodone-d8) Labelled Vilazodone. It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.;Labeled Vilazodone, intended for use as an in
The Uses of Vilazodone-d8
Labelled Vilazodone (V265000). It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.
Properties of Vilazodone-d8
Melting point: | 195-198°C |
storage temp. | Refrigerator |
solubility | Water: 0.32 mg/ml |
form | A solid |
color | White to off-white |
Safety information for Vilazodone-d8
Computed Descriptors for Vilazodone-d8
New Products
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