VALNEMULIN
- CAS NO.：101312-92-9
- Empirical Formula: C31H52N2O5S
- Molecular Weight: 564.82
- MDL number: MFCD09832850
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:08
What is VALNEMULIN?
Description
Valnemulin is a broad-spectrum pleuromutilin antibiotic that binds to peptidyl transferase in the 50S ribosomal subunit. It has been used in veterinary medicine to treat swine diseases including, B. hyodysenteriae and M. hyopneumoniae.
Chemical properties
White to Off-White Solid
The Uses of VALNEMULIN
Valnemulin is a semi-synthetic pleuromutilin prepared by sequential reaction of pleuromutilin tosylate with 2-amino-1,1-dimethylethylthiol, coupling the free amine with a protected valine and then deprotection to provide the final product. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA.
The Uses of VALNEMULIN
Semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial
Properties of VALNEMULIN
| Melting point: | 140-143°C |
| Boiling point: | 672.7±55.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble |
| form | A solid |
| pka | 14.65±0.70(Predicted) |
Safety information for VALNEMULIN
Computed Descriptors for VALNEMULIN
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