Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

CAS NO.：2428400-33-1
Empirical Formula: C24H31N3O6
Molecular Weight: 457.52
MDL number: MFCD34469879
Update Date: 2024-07-02 08:55:38

What is Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-?

Biological Activity

Thalidomide-NH-C10-COOH (compound 6b) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based von Hippel-Lindau (VHL) ligand and a linker used in PROTAC technology[1].

References

[1]. Kim K, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019 Dec 23;9(1):19654.

Properties of Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Boiling point:	718.9±55.0 °C(Predicted)
Density	1.303±0.06 g/cm3(Predicted)
pka	4.78±0.10(Predicted)
form	Solid
color	Light yellow to yellow

Safety information for Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Computed Descriptors for Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

New Products

6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin E Tubulysin G Tubulysin H Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Calcium Sodium Phosphosilicate IH 3,6-Bis(4-bromophenyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione Diethyl 2,5-di(furan-2-yl)terephthalate 3-Morpholino-5,6-dihydropyridin-2(1H)-one Methyl 4-amino-3-(4-phenylpiperazin-1-yl)benzoate 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 7-(1,1-Dimethylethyl) 7-azaspiro[3.5]nonane-2,7-dicarboxylate 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine (4R,12aR)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1`,2`;4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid

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