U-74389G
Synonym(s):21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt
- CAS NO.:153190-29-5
- Empirical Formula: C41H54N6O6
- Molecular Weight: 726.9
- MDL number: MFCD01074991
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is U-74389G?
Description
U-
The Uses of U-74389G
U-74389G is a potent inhibitor of superoxide-mediated lipid peroxidation.
What are the applications of Application
U-74389G is a potent inhibitor of superoxide-mediated lipid peroxidation
References
1) Braughler et al. (1987) Novel 21-aminosteroids as potent inhibitors of iron-dependent lipid peroxidation; J. Biol. Chem., 262 10438 2) Campo et al. (1996) Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation; J. Pharmacol. Exp. Ther., 277 333 3) Perna et al. (1996) Protection of rat heart from ischaemia-reperfusion injury by the 21-aminosteroid U-74389G; Pharmacol. Res., 34 25
Properties of U-74389G
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | ethanol: soluble20 mg/mL, clear, light yellow |
form | White solid. |
color | White |
Sensitive | Hygroscopic |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Safety information for U-74389G
Computed Descriptors for U-74389G
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