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HomeProduct name listTylosin phosphate

Tylosin phosphate

  • CAS NO.:1405-53-4
  • Empirical Formula: C46H80NO21P
  • Molecular Weight: 1014.11
  • MDL number: MFCD06795692
  • EINECS: 215-779-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-29 17:54:24
Tylosin phosphate  Structural

What is Tylosin phosphate ?

Chemical properties

Tylosin phosphate (TS) is a light yellow to yellow liquid substance with a characteristic odor.
Tylosin phosphate
Tylosin phosphate has an antibacterial effect mainly on Gram-positive bacteria and partly on Gramnegative bacteria and mycoplasma, and has a growth-promoting effect on pigs.

The Uses of Tylosin phosphate

Tylosin phosphate is a pure-grade antibiotic that was designated as a feed additive as of July 24, 1976. It is used for prevention and control of chronic respiratory disease (CRD) in replacement pullets, broilers, increasing bodyweight and improvement of feed conversion rate in broilers, increasing egg production.

What are the applications of Application

Tylosin phosphate is an antibacterial agent employed against mycoplasma organisms

General Description

Tylosin phosphate is an antibacterial agent employed against mycoplasma organisms. It is only used in veterinary field and effective basically against gram positive bacteria, but also has efficacy against some spirochetes and gram negatives (except coliforms). Tylosin phosphate, marketed as Tylan 40 or Tylan 100 Type A medicated article, is approved for use in beef cattle to reduce the incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.

Mechanism of action

Tylosin phosphate is an antibiotic of macrolide group which is produced by fermentation of a certain fungus. This antibiotic prevents protein synthesis by ribosomes and thus prevents bacterial growth, resulting in their death. Special mechanism of action of macrolides, besides stopping rapid growth of microorganisms prevents buildup of bacterial resistance.

Properties of Tylosin phosphate

Melting point: >128°C (dec.)
storage temp.  2-8°C
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Solid
form  neat
color  Pale Yellow
Stability: Hygroscopic
CAS DataBase Reference 1405-53-4(CAS DataBase Reference)

Safety information for Tylosin phosphate

Signal word Danger
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H317:Sensitisation, Skin
H334:Sensitisation, respiratory
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P272:Contaminated work clothing should not be allowed out of the workplace.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P284:Wear respiratory protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

Computed Descriptors for Tylosin phosphate

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