Tussilagone
- CAS NO.：104012-37-5
- Empirical Formula: C23H34O5
- Molecular Weight: 390.51
- MDL number: MFCD32004666
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-17 16:00:36
What is Tussilagone?
Chemical properties
White crystalline powder, soluble in ether, chloroform, ethyl acetate, methanol, insoluble in water, derived from the flower bud of Asteraceae Tussilago farfara, Senecio kleinia Less root.
Biological Activity
Tussilagone, the main active ingredient of Tussilago farfara, has anti-inflammatory properties. It ameliorates the inflammatory response of dextran sulfate sodium-induced colitis in mice.
in vivo
Tussilagone administration (1 mg/kg and 10 mg/kg) produced decreased mortality and lung injury in CLP-activated septic mice. Augmented expression of cyclooxygenase (COX)-2 and TNF-α in pulmonary alveolar macrophages of septic mice were attenuated by tussilagone administration.
Properties of Tussilagone
| Boiling point: | 471.3±35.0 °C(Predicted) |
| Density | 1.07±0.1 g/cm3 (20 ºC 760 Torr) |
| form | Solid |
| color | White to off-white |
Safety information for Tussilagone
Computed Descriptors for Tussilagone
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