Triptonide
Synonym(s):14-deoxy-14-oxo-triptolide;Triptonide
- CAS NO.：38647-11-9
- Empirical Formula: C20H22O6
- Molecular Weight: 358.39
- MDL number: MFCD00210566
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-04 20:04:50
What is Triptonide?
The Uses of Triptonide
Triptonide is a Triptolide (T815600) analogue used in the preparation of cytotoxic fluorinated Triptolide.
Definition
ChEBI: Triptonide is a diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. It has a role as an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent. It is a cyclic ketone, an organic heteroheptacyclic compound, a diterpene triepoxide and a butenolide.
Properties of Triptonide
| Melting point: | 251～252℃ |
| Boiling point: | 581.1±50.0 °C(Predicted) |
| Density | 1.48±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Dichloromethane (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Beige |
Safety information for Triptonide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Triptonide
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