Triethylenetetramine Dihydrochloride
Synonym(s):N,N′-Bis(2-aminoethyl)-1,2-ethanediamine dihydrochloride;Triethylenetetramine dihydrochloride
- CAS NO.：38260-01-4
- Empirical Formula: C6H20Cl2N4
- Molecular Weight: 219.16
- MDL number: MFCD00012889
- EINECS: 253-854-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-05 20:42:10
What is Triethylenetetramine Dihydrochloride?
Description
Trientine hydrochloride is a copper chelating agent recommended for the treatment of Wilson's Disease, especially in patients intolerant of penicillamine therapy. Unlike the latter agent, trientine is not indicated in cystinuria or rheumatoid arthritis.
Chemical properties
white crystalline powder
Originator
Cambridge University (United Kingdom)
The Uses of Triethylenetetramine Dihydrochloride
antibacterial
The Uses of Triethylenetetramine Dihydrochloride
As thermosetting resin; epoxy curing agent; lubricating oil additive; analytical reagent for Cu, Ni.
The Uses of Triethylenetetramine Dihydrochloride
Triethylenetetramine Hydrochloride is a selective CuII-chelator; crosslinking agent. Triethylenetetramine is undergoing trials for the treatment of heart failure in patients with diabetes.
Definition
ChEBI: Trientine hydrochloride is a secondary amino compound.
brand name
Syprine (Merck);CUPRID.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Trientine Hydrochloride is administered for relief of symptoms of Wilson′s disease for penicillamine intolerance, hence is employed as an oral medication for the treatment of an inherited defect in copper metabolism.
Properties of Triethylenetetramine Dihydrochloride
| Melting point: | 120-125 °C (dec.) |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| BRN | 5961763 |
Safety information for Triethylenetetramine Dihydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H317:Sensitisation, Skin H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
Computed Descriptors for Triethylenetetramine Dihydrochloride
Triethylenetetramine Dihydrochloride manufacturer
Nuray Chemicals Pvt Ltd
Apothecon Pharmaceuticals Pvt Ltd
Ralington Pharma
Biophore India Pharmaceuticals Pvt Ltd
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