trans-Cevimeline Hydrochloride
- CAS NO.：107220-29-1
- Empirical Formula: C10H18ClNOS
- Molecular Weight: 235.77402
- MDL number: MFCD01961046
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:44:00
What is trans-Cevimeline Hydrochloride?
Description
trans-Cevimeline HCl, also known as AF 102A, is the trans-isomer of AF102B (Cevimeline). Cevimeline is a cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds to and activates muscarinic receptors, thereby increasing the secretions in exocrine salivary and sweat glands. This cholinergic agonist also increases the tone of smooth muscle in the gastrointestinal and urinary tracts. Cevimeline is being studied as a treatment for dry mouth caused by radiation therapy to the head and neck.
The Uses of trans-Cevimeline Hydrochloride
trans-Cevimeline Hydrochloride is a reagent in the preparation of spiro-oxathiolane/quinuclidine sulfoxide derivative for the treatment of central nervous and cholinergic system disease or disorders.
Properties of trans-Cevimeline Hydrochloride
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for trans-Cevimeline Hydrochloride
Computed Descriptors for trans-Cevimeline Hydrochloride
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