Tiletamine hydrochloride

Chemical properties

Tiletamine hydrochloride is the salt form of Tiletamine , exists as odorless white crystals or White to Off-White Solid. It is mainly used for closed anesthesia and general anesthesia.?

The Uses of Tiletamine hydrochloride

Tiletamine is a receptor antagonist, an anesthetic drug. Tiletamine is related chemically and pharmacologically to other anesthetics in this family such as ketamine and phencyclidine.

Indications

Tiletamine hydrochloride/zolazepam hydrochloride is used for chemical immobilization and surgical anesthesia in a wide variety of carnivores, artiodactylids, birds, reptiles, and amphibians.

Veterinary Drugs and Treatments

Telazol® is indicated for restraint or anesthesia combined with muscle relaxation in cats, and for restraint and minor procedures of short duration (≈30 minutes) which require mild to moderate analgesia in dogs. Although not officially approved, it has been used also in horses and many exotic and wild species.

Mode of action

Tiletamine hydrochloride is a dissociative anesthetic agent whose pharmacologic action is characterized by profound analgesia, normal pharyngeal-laryngeal reflexes and cataleptoid anesthesia. Used alone, tiletamine hydrochloride does not provide adequate muscle relaxation for abdominal surgical procedures. When combined with zolazepam hydrochloride, good muscle relaxation is generally attained during the phase of deep surgical anesthesia. Tilzolan is a rapid-acting anesthetic combination of tiletamine hydrochloride and zolazepam hydrochloride.