Tiapride
- CAS NO.:51012-32-9
- Empirical Formula: C15H24N2O4S
- Molecular Weight: 328.43
- MDL number: MFCD00242730
- EINECS: 256-907-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is Tiapride?
Originator
Tiapridal,Delagrange,France,1977
The Uses of Tiapride
Tiapride hydrochloride is a D2DR and D3DR inhibitor; Anti-psychotic agent and alternative treatment for Tourette’s syndrome.
The Uses of Tiapride
diuretic, antihypertensive
Definition
ChEBI: N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide is a member of benzamides.
Manufacturing Process
5 g of 2-methoxy-5-methylsulfonylbenzoic acid, 50 ml of dioxan, 3.02 ml of
triethylamine and 3 g of isobutyl chloroformate were introduced into a 250 ml
balloon flask at ambient temperature.
After the mixture had been stirred for 30 minutes, 3 g of N,N_x0002_diethylethylenediamine were added. The reaction mixture was stirred for 6
hours and the solvents were evaporated under vacuum.
The residue was dissolved in 50 ml of water and the solution was made
alkaline with sodium hydroxide. The precipitate formed was filtered, washed
and dried in a drying oven at 60°C. 6 g of N-(diethylaminoethyl)-2-methoxy-
5-methylsulfonylbenzamide (melting point: 124°C to 125°C) was produced.
brand name
Tiapride Hydrochloride is JAN.
Therapeutic Function
Antiemetic
Properties of Tiapride
Melting point: | 123-125° |
vapor pressure | 0Pa at 25℃ |
storage temp. | 2-8°C |
pka | 9.14[at 20 ℃] |
Water Solubility | 349mg/L at 25℃ |
CAS DataBase Reference | 51012-32-9(CAS DataBase Reference) |
Safety information for Tiapride
Computed Descriptors for Tiapride
Related products of tetrahydrofuran
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