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HomeProduct name listTiapride

Tiapride

  • CAS NO.:51012-32-9
  • Empirical Formula: C15H24N2O4S
  • Molecular Weight: 328.43
  • MDL number: MFCD00242730
  • EINECS: 256-907-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
Tiapride Structural

What is Tiapride?

Originator

Tiapridal,Delagrange,France,1977

The Uses of Tiapride

Tiapride hydrochloride is a D2DR and D3DR inhibitor; Anti-psychotic agent and alternative treatment for Tourette’s syndrome.

The Uses of Tiapride

diuretic, antihypertensive

Definition

ChEBI: N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide is a member of benzamides.

Manufacturing Process

5 g of 2-methoxy-5-methylsulfonylbenzoic acid, 50 ml of dioxan, 3.02 ml of triethylamine and 3 g of isobutyl chloroformate were introduced into a 250 ml balloon flask at ambient temperature.
After the mixture had been stirred for 30 minutes, 3 g of N,N_x0002_diethylethylenediamine were added. The reaction mixture was stirred for 6 hours and the solvents were evaporated under vacuum.
The residue was dissolved in 50 ml of water and the solution was made alkaline with sodium hydroxide. The precipitate formed was filtered, washed and dried in a drying oven at 60°C. 6 g of N-(diethylaminoethyl)-2-methoxy- 5-methylsulfonylbenzamide (melting point: 124°C to 125°C) was produced.

brand name

Tiapride Hydrochloride is JAN.

Therapeutic Function

Antiemetic

Properties of Tiapride

Melting point: 123-125°
vapor pressure  0Pa at 25℃
storage temp.  2-8°C
pka 9.14[at 20 ℃]
Water Solubility  349mg/L at 25℃
CAS DataBase Reference 51012-32-9(CAS DataBase Reference)

Safety information for Tiapride

Computed Descriptors for Tiapride

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