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HomeProduct name listThiosildenafil

Thiosildenafil

Thiosildenafil Structural

What is Thiosildenafil?

Description

Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .

Chemical properties

Pale Yellow Solid

The Uses of Thiosildenafil

Sildenafil, marketed under the trade name Viagra?, is a potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. Thiosildenafil is a derivative of sildenafil that has been found as an adulterant in dietary supplements advertising sexual enhancement for men. The biological characteristics of thiosildenadil have not been reported.[Cayman Chemical]

The Uses of Thiosildenafil

An analog of Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

The Uses of Thiosildenafil

An analog of labelled Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.

What are the applications of Application

Thiosildenafil is a PDE5A inhibitor

Properties of Thiosildenafil

Melting point: 172-174?C
Boiling point: 676.1±65.0 °C(Predicted)
Density  1.39±0.1 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form  Solid
pka 5.97±0.42(Predicted)
color  Pale Yellow to Light Yellow

Safety information for Thiosildenafil

Computed Descriptors for Thiosildenafil

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