THIOFORMAMIDE
- CAS NO.:115-08-2
- Empirical Formula: CH3NS
- Molecular Weight: 61.11
- MDL number: MFCD07787620
- EINECS: 204-063-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:32
What is THIOFORMAMIDE?
The Uses of THIOFORMAMIDE
Thioformamide, can be used in the synthesis of sulfoximine tethered heterocycles used as key building blocks.
Purification Methods
Crystallise thioformamide from EtOAc, Et2O or ether/pet ether. The monohydrate is a yellow oil soluble in many organic solvents. UV: 263nm ( 2500) in MeOH. [Erlenmyer & Menzi Helv Chim Acta 31 2071 1948.] Alternatively dissolve it in Et2O to separate it from any formanide and/or polymers, filter, evaporate and recrystallise the residue from EtOAc at Dry-Ice temperature [Londergan et al. J Am Chem Soc 75 4456 1953]. Store it in Et2O solution over P2O5. [Cousineau & Secrist J Org Chem 44 4351 1979, Beilstein 2 H 95, 2 I 39, 2 III 128, 2 IV 92.]
Properties of THIOFORMAMIDE
Melting point: | 28-29℃ |
Boiling point: | 105℃ |
Density | 1.133 |
Flash point: | 17℃ |
solubility | DMSO (Sparingly), THF (Soluble) |
form | Colourless to Dark Brown Solution |
pka | 12.60±0.29(Predicted) |
Safety information for THIOFORMAMIDE
Computed Descriptors for THIOFORMAMIDE
New Products
TIN AAS SOLUTION SILVER AAS SOLUTION ANDRADES REAGENT SOLUTION GRAMS SAFRANINE STAINING SOLUTION PLATINUM AAS SOLUTION TUNGSTEN AAS SOLUTION Folic Acid Impurity G Desloratidine Related compound B Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
4-METHOXYPHENYLTHIOUREA
N-ACETYLTHIOUREA
1-(2-NAPHTHYL)-2-THIOUREA
N-METHYLTHIOUREA
4-METHYL-5-(TRIFLUOROMETHYL)-1,2,4-TRIAZOLIN-3(2H)-THIONE
1-BENZYL-3-METHYL-2-THIOUREA
1,3-Dibutyl-2-thiourea
N,N'-DICYCLOHEXYLDITHIOOXAMIDE
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