Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listTETRANOR-12(S)-HETE

TETRANOR-12(S)-HETE

TETRANOR-12(S)-HETE Structural

What is TETRANOR-12(S)-HETE?

Description

12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix. tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE in numerous tissues, and Lewis lung carcinoma cells. No biological function has yet been determined for tetranor-12(S)-HETE. Some data indicate it may play a role in controlling the inflammatory response in injured corneas. In some diseases (e.g., Zellweger’s Syndrome) peroxisomal abnormalities result in the inability of cells to metabolize 12(S)-HETE, which may be responsible for symptoms of the disease. The tetranor derivative of 12(S)-HETE is available as a research tool for the elucidation of the metabolic fate of its parent compound.

What are the applications of Application

tetranor-12(S)-HETE is a derivative of 12(S)-HETE

Definition

ChEBI: Tetranor 12-HETE is a hydroxy fatty acid.

Properties of TETRANOR-12(S)-HETE

storage temp.  Store at -20°C
solubility  0.1 M Na2CO3: 2 mg/ml; DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): .5 mg/ml

Safety information for TETRANOR-12(S)-HETE

Computed Descriptors for TETRANOR-12(S)-HETE

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.