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HomeProduct name listTETRAHYDROCORTISOL

TETRAHYDROCORTISOL

Synonym(s):THF;Urocortisol;5β-Tetrahydrocortisol;Tetrahydro F;Tetrahydrocompound F

  • CAS NO.:53-02-1
  • Empirical Formula: C21H34O5
  • Molecular Weight: 366.49
  • MDL number: MFCD00067597
  • EINECS: 200-159-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-18 11:31:09
TETRAHYDROCORTISOL Structural

What is TETRAHYDROCORTISOL?

The Uses of TETRAHYDROCORTISOL

Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.

What are the applications of Application

Tetrahydrocortisol is a metabolite of cortisol.

Definition

ChEBI: Tetrahydrocortisol is a 3alpha-hydroxy steroid, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a glucocorticoid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It derives from a hydride of a 5beta-pregnane.

Properties of TETRAHYDROCORTISOL

Melting point: −108 °C(lit.)
Boiling point: 65-67 °C(lit.)
Density  0.889 g/mL at 25 °C(lit.)
vapor density  2.5 (vs air)
vapor pressure  114 mm Hg ( 15 °C)
refractive index  n20/D 1.407(lit.)
Flash point: 1 °F
storage temp.  2-8°C
solubility  Chloroform (Very Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Sligh
form  Solid
pka 12.48±0.70(Predicted)
color  <10(APHA)
Stability: Hygroscopic

Safety information for TETRAHYDROCORTISOL

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for TETRAHYDROCORTISOL

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