(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate
- CAS NO.：30392-41-7
- Empirical Formula: C45H64N2O5S
- Molecular Weight: 745.06506
- MDL number: MFCD01679558
- EINECS: 250-177-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
![(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate Structural](https://img.chemicalbook.in/CAS/GIF/30392-41-7.gif)
What is (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate?
Description
Bitolterol is a prodrug that releases colterol on activation by esterases in the lung. Colterol is a direct-acting agonist, and the N-t-butyl group makes it β2-selective with a binding potency equivalent to that of isoetharine and terbutaline. The ester form is lipophilic, which helps to keep it local in the lung and resistant to COMT, which tends to increase its duration of action. Onset begins 2 to 4 minutes after administration, and the effect can last as long as 8 hours. It has a adverse effect profile similar to that of other β2-selective agonists, with less drowsiness and restlessness compared to other direct-acting agonists.
The Uses of (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate
β2-adrenergic receptor agonist
Definition
ChEBI: The methanesulfonate salt of bitolterol. A beta2-adrenergic receptor agonist, it is used for relief of bronchospasm in conditions such as asthma, chronic bronchitis and emphysema.
brand name
Tornalate (Sanofi Aventis).
Properties of (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate
| Melting point: | 170-172° |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Light Beige |
Safety information for (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate
Computed Descriptors for (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 4-Hydrazinobenzoic acid 3,4-Dibenzyloxybenzaldehyde 3-Nitrobenzaldehyde 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) 4-HYDROXY BENZYL ALCOHOL 3-NITRO-2-METHYL ANILINE (2-Hydroxyphenyl)acetonitrile 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride tert-butyl 4- (ureidomethyl)benzylcarbamate diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
873-83-6 6-Aminouracil (or) 4-Amino-2,6- dihydroxypyrimidine, (or) 6-Amino2,4-pyrimidinediol 99%View Details
873-83-6 -
55441-95-7 99%View Details
55441-95-7 -
N-Vinylformamide 99%View Details
13162-05-5 -
Chloro Uracil 1820-81-1 99%View Details
1820-81-1 -
207557-35-5 99%View Details
207557-35-5 -
2-ethyl-6-methyl-3-hydroxypyridine succinate 99%View Details
127464-43-1 -
2-ETHYLPYRIDINE 100-71-0 99%View Details
100-71-0 -
181228-33-1 (S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanote Hydrochloride (DAP-OMe. HCl) 99%View Details
181228-33-1