Boc-His(Trt)-Aib-OH

CAS NO.：2061897-68-3
Empirical Formula: C34H38N4O5
Molecular Weight: 582.7
MDL number: MFCD32173661
Update Date: 2024-03-27 13:09:27

What is Boc-His(Trt)-Aib-OH?

The Uses of Boc-His(Trt)-Aib-OH

Boc-His(Trt)-Aib-OH is a peptide that can be synthesized from Boc-His(Trt)-OH (32926-43-5).

Biosynthesis

Boc-His(Trt)-Aib-OH is a peptide that can be synthesized from Boc-His(Trt)-OH.

Synthesis

4.3 g of Boc-L-His(Trt)-Aib-OBzl were dissolved in 30 ml THF and 3 ml of ethyl acetate. 0.43 g of the hydrogenation catalyst Pd/C (5%) was added and the compound was hydrogenated at 30° C for 2 h at atmospheric hydrogen pressure using a balloon. The catalyst is filtered oil and washed with 30 ml of ethyl acetate. The solution was stirred for several hours until precipitation occurred. The precipitate is filtered off and dried under vacuum to obtain 2.45 g of Boc-His(Trt)-Aib-OH.

Properties of Boc-His(Trt)-Aib-OH

Boiling point:	789.3±60.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
solubility	Chloroform (Slightly), DMSO (Slightly)
pka	3.43±0.10(Predicted)
form	Solid
color	White to Off-White

Safety information for Boc-His(Trt)-Aib-OH

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.