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HomeProduct name listTebufenpyrad

Tebufenpyrad

Synonym(s):4-Chloro-N-(4-tert-butylbenzyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide

  • CAS NO.:119168-77-3
  • Empirical Formula: C18H24ClN3O
  • Molecular Weight: 333.86
  • MDL number: MFCD01632408
  • EINECS: 242-070-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-08-18 13:05:06
Tebufenpyrad Structural

What is Tebufenpyrad?

Chemical properties

Tan Solid

The Uses of Tebufenpyrad

Tebufenpyrad is a pyrazole acaricide and insecticide commonly used in commercial greenhouses.

The Uses of Tebufenpyrad

Acaricide.

Definition

ChEBI: Tebufenpyrad is a pyrazole acaricide and a pyrazole insecticide. It has a role as a mitochondrial NADH:ubiquinone reductase inhibitor.

Metabolic pathway

By incubation of tebufenpyrad with rat liver homogenate, tebufenpyrad undergoes biotransformation to yield the major metabolites N-(4- tert-butylbenzyl)-4-chloro-3-(1-hydroxyethyl)-1- methylpyrazole-5-carboxamide via hydroxylation of the w-1-carbon of the ethyl group and N-[4-(1-carboxy-1- methylethyl)benzyl]-4-chloro-3-ethyl-1-methylpyrazole- 5-carboxamide via oxidation of the methyl group in the tert-butyl moiety to the carboxylic acid derivatives.
When the rat is orally dosed tebufenpyrad, the major metabolism pathway is via both hydroxylation and oxidation reactions to yield N-[4-(1-carboxy-1- methylethyl)benzyl]-4-chloro-3-(1-hydroxyethyl)-1- methylpyrazole-5-carboxamide which is mainly excreted in the urine.

Properties of Tebufenpyrad

Melting point: 61-62°
Boiling point: 468.4±45.0 °C(Predicted)
Density  1.1639 (rough estimate)
refractive index  1.5790 (estimate)
storage temp.  0-6°C
solubility  Benzene (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 13.19±0.46(Predicted)
form  neat
BRN  8636471
CAS DataBase Reference 119168-77-3(CAS DataBase Reference)
EPA Substance Registry System Tebufenpyrad (119168-77-3)

Safety information for Tebufenpyrad

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H301:Acute toxicity,oral
H317:Sensitisation, Skin
H332:Acute toxicity,inhalation
H373:Specific target organ toxicity, repeated exposure
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P314:Get medical advice/attention if you feel unwell.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352:IF ON SKIN: wash with plenty of soap and water.

Computed Descriptors for Tebufenpyrad

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