TAUTOMYCETIN SOLUTION
- CAS NO.：119757-73-2
- Empirical Formula: C33H50O10
- Molecular Weight: 606.75
- MDL number: MFCD01750322
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is TAUTOMYCETIN SOLUTION?
The Uses of TAUTOMYCETIN SOLUTION
Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells. Tautomycin is closely related to another anhydride containing polyketide PP inhibitor called Tautomycetin which, in addition to being useful as a lead for cancer drug discovery, also is a very potent immunosuppressor.
Definition
ChEBI: Tautomycetin is a sesquiterpenoid.
Biological Activity
Potent activated T cell-specific immunosuppressor. Selectively inhibits PP1 over PP2 with IC 50 values of 1.6 and 62 nM respectively. Active in vivo .
Properties of TAUTOMYCETIN SOLUTION
| Boiling point: | 763.7±60.0 °C(Predicted) |
| Density | 1.148±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: 10 mg/mL |
| form | Colourless liquid |
| pka | 12.36±0.20(Predicted) |
| color | colorless |
Safety information for TAUTOMYCETIN SOLUTION
Computed Descriptors for TAUTOMYCETIN SOLUTION
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