TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Synonym(s):3α,7β-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide;Tauroursodeoxycholic acid sodium salt
- CAS NO.:35807-85-3
- Empirical Formula: C26H46NNaO6S
- Molecular Weight: 523.7
- MDL number: MFCD00065451
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is TAUROURSODEOXYCHOLIC ACID SODIUM SALT?
Chemical properties
Off-White Solid
The Uses of TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Tauroursodeoxycholic Acid Sodium Salt is a bile related salt for isolation of lipids and membrane-bound proteins. It is a sodium salt form of Tauroursodeoxycholic Acid which can be used in biological study of inhibition of alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption by glycyrrhizin and glycyrrhetinic acid.
The Uses of TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.
The Uses of TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Sodium tauroursodeoxycholate has been used in a study to assess whether ER stress is involved in palmitic acid upregulation (PA). It has also been used in a study to investigate its effect on Estradiol-17β-D-glucuronide (E-17G) induced cholestasis in female rats.
General Description
Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.
Properties of TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Melting point: | 173-175°C |
alpha | +40~+50°(D/20℃) |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | DMSO (Slightly, Heated), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
form | Solid |
color | Off-White to Pale Beige |
Safety information for TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P313:Get medical advice/attention. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for TAUROURSODEOXYCHOLIC ACID SODIUM SALT
InChIKey | WSSCRQYICWZEFG-SXXADWEANA-N |
SMILES | C[C@]12CC[C@]3([H])[C@]4(CC[C@@H](O)C[C@@]4([H])C[C@H](O)[C@@]3([H])[C@]1([H])CC[C@]2([H])[C@H](C)CCC(=O)NCCS(O)(=O)=O)C.[NaH] |&1:1,4,6,9,12,15,17,19,23,25,r| |
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