SULFO-SMCC
Synonym(s):SMCC, Water-Soluble;Sulfo-SMCC;Sulfosuccinimidyl- trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC;Sulfosuccinimidyl-trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC
- CAS NO.:92921-24-9
- Empirical Formula: C16H19N2NaO9S
- Molecular Weight: 438.38
- MDL number: MFCD00054978
- EINECS: 618-887-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is SULFO-SMCC?
Description
Sulfo-SMCC is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
Chemical properties
Solid
The Uses of SULFO-SMCC
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms
The Uses of SULFO-SMCC
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms
What are the applications of Application
Sulfo-SMCC is a sulfhydryl- and amine-reactive crosslinker
Properties of SULFO-SMCC
Melting point: | >270°C (dec.) |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | H2O: soluble2.5mg/mL |
form | powder |
color | white to light brown |
Water Solubility | Soluble in water (2.5 mg/ml) and dimethyl formamide. |
Stability: | Moisture Sensitive |
Safety information for SULFO-SMCC
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for SULFO-SMCC
InChIKey | VUFNRPJNRFOTGK-UHFFFAOYSA-M |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
1-HEXYL-PYRROLE-2,5-DIONE
N-Hydroxysulfosuccinimide sodium salt
(Aminomethyl)cyclohexane
2-PROPANESULFONIC ACID SODIUM SALT
N-Succinimidyl 6-maleimidohexanoate
N-METHYLTAURINE SODIUM SALT
ACRYLOYL-X, SE
N-(CYCLOHEXYLMETHYL)DIETHYL AMINO
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