SULFO-SMCC

Synonym(s):SMCC, Water-Soluble;Sulfo-SMCC;Sulfosuccinimidyl- trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC;Sulfosuccinimidyl-trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC

CAS NO.：92921-24-9
Empirical Formula: C16H19N2NaO9S
Molecular Weight: 438.38
MDL number: MFCD00054978
EINECS: 618-887-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-08 20:21:46

What is SULFO-SMCC?

Description

Sulfo-SMCC is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

Chemical properties

Solid

The Uses of SULFO-SMCC

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms

The Uses of SULFO-SMCC

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms

What are the applications of Application

Sulfo-SMCC is a sulfhydryl- and amine-reactive crosslinker

Properties of SULFO-SMCC

Melting point:	>270°C (dec.)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	H2O: soluble2.5mg/mL
form	powder
color	white to light brown
Water Solubility	Soluble in water (2.5 mg/ml) and dimethyl formamide.
Stability:	Moisture Sensitive

Safety information for SULFO-SMCC

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.