Sulfacetamide sodium

Synonym(s):Sulfacetamide sodium salt;Sulfacetamide sodium salt monohydrate

CAS NO.：127-56-0
Empirical Formula: C8H9N2NaO3S
Molecular Weight: 236.22
MDL number: MFCD00007885
EINECS: 204-848-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-19 17:35:41

What is Sulfacetamide sodium ?

Description

Sulfacetamide is a sulfonamide antibiotic that is bacteriostatic against Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (IC₅₀ = 9.6 μM), blocking the synthesis of dihydrofolic acid, and also inhibits bacterial 4-aminobenzoic acid , which is required for the synthesis of folic acid.

The Uses of Sulfacetamide sodium

Sulfacetamide Sodium is an anti-biotic

The Uses of Sulfacetamide sodium

Sulfacetamide Sodium Salt is an antibiotic that blocks synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. It can be used in biological study to explore topical application of benzoyl peroxide, antibiotics, sulfur and sodium sulfacetamide, azelaic acid for treatment of acne vulgaris in humans.

What are the applications of Application

Sulfacetamide sodium salt is an antibiotic that blocks synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase

Definition

ChEBI: An organic sodium salt that is the monosodium salt of sulfacetamide.

brand name

Bleph (Allergan); Cetamide (Alcon); Klaron (Sanofi Aventis); Ocusulf (MIZA); Sodium Sulamyd (Schering); Sulf (Novartis); Sulfacel (Optopics); Sulfair (Pharmafair); Sulten (Bausch & Lomb).

Properties of Sulfacetamide sodium

Melting point:	257 °C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Water Solubility	Soluble in water
solubility	DMF: 20 mg/mL; DMSO: 15 mg/mL; Ethanol: 1 mg/mL; PBS (pH 7.2): 5 mg/mL
form	Solid
form	neat
color	White to Almost white
Merck	14,8899
CAS DataBase Reference	127-56-0
EPA Substance Registry System	Acetamide, N-[(4-aminophenyl)sulfonyl]-, monosodium salt (127-56-0)

Safety information for Sulfacetamide sodium

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.