STRYCHNINE HYDROCHLORIDE
- CAS NO.：1421-86-9
- Empirical Formula: C21H23ClN2O2
- Molecular Weight: 370.87
- MDL number: MFCD00058174
- EINECS: 215-826-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:55
What is STRYCHNINE HYDROCHLORIDE?
The Uses of STRYCHNINE HYDROCHLORIDE
Strychnine Hydrochloride acts as an antagonist for cholinesterases and beta amyloid aggregation.
The Uses of STRYCHNINE HYDROCHLORIDE
Strychnine hydrochloride has been used as a glycine receptor antagonist in the retina for biophysiological functions. It has also been used to block glutamatergic, GABAergic and glycinergic receptors and gap junctions.
Definition
ChEBI: A hydrochloride obtained by combining strychnine with one molar equivalent of hydrogen chloride.
Biological Activity
Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α 7 receptors and non-competitive antagonism at α 4 β 2 receptors.
Biochem/physiol Actions
Strychnine is a potent convulsant, which is extracted from Strychnos nux vomica seeds. At high doses, the compound causes convulsions and ultimately death due to respiratory paralysis. Strychnine acts as a respiratory, circulatory and digestive stimulant.
Properties of STRYCHNINE HYDROCHLORIDE
| Melting point: | 295 °C |
| storage temp. | Store at RT |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Sparingly, Slightly) |
| form | Solid |
| color | White to Light Beige |
| Merck | 14,8855 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 1421-86-9(CAS DataBase Reference) |
| EPA Substance Registry System | Strychnine hydrochloride (1421-86-9) |
Safety information for STRYCHNINE HYDROCHLORIDE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. |
Computed Descriptors for STRYCHNINE HYDROCHLORIDE
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