stephanine
- CAS NO.：517-63-5
- Empirical Formula: C19H19NO3
- Molecular Weight: 309.36
- MDL number: MFCD00238687
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is stephanine?
Description
l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76. Stephanine and crebanine have high inhibitory activity against gram-positive animal pathogenic bacteria, with MIC values of 0.078-0.312g/l, but low inhibitory activity against gram-negative animal pathogenic bacteria, they also inhibit hyphal growth of the plant pathogens Cercospora kaki. 3. Stephanine, pseudopalmatine , tetrahydropalmatine , and xylopinine show significant antiplasmodial activities with IC(50) ranged from 2 uM to 53 uM.
Properties of stephanine
| Melting point: | 155 °C |
| Boiling point: | 463.6±45.0 °C(Predicted) |
| Density | 1.268±0.06 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Cryst. |
| pka | 7.03±0.20(Predicted) |
Safety information for stephanine
Computed Descriptors for stephanine
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