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stephanine

  • CAS NO.:517-63-5
  • Empirical Formula: C19H19NO3
  • Molecular Weight: 309.36
  • MDL number: MFCD00238687
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
stephanine Structural

What is stephanine?

Description

l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76. Stephanine and crebanine have high inhibitory activity against gram-positive animal pathogenic bacteria, with MIC values of 0.078-0.312g/l, but low inhibitory activity against gram-negative animal pathogenic bacteria, they also inhibit hyphal growth of the plant pathogens Cercospora kaki. 3. Stephanine, pseudopalmatine , tetrahydropalmatine , and xylopinine show significant antiplasmodial activities with IC(50) ranged from 2 uM to 53 uM.

Properties of stephanine

Melting point: 155 °C
Boiling point: 463.6±45.0 °C(Predicted)
Density  1.268±0.06 g/cm3(Predicted)
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Cryst.
pka 7.03±0.20(Predicted)

Safety information for stephanine

Computed Descriptors for stephanine

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