SR27897
- CAS NO.：136381-85-6
- Empirical Formula: C20H14ClN3O3S
- Molecular Weight: 411.86
- MDL number: MFCD21608519
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-08 20:21:46
What is SR27897?
The Uses of SR27897
SR 27897 is a human cholecystokinin type 1 (CCK1) competitive antagonist.
What are the applications of Application
SR 27897 is an effective non-peptide antagonist of CCK
Definition
ChEBI: 2-[2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]-oxomethyl]-1-indolyl]acetic acid is an indolyl carboxylic acid.
Biological Activity
Potent, non-peptide CCK 1 receptor antagonist that displays > 33-fold selectivity over CCK 2 receptors (EC 50 values are 6 and 200 nM respectively). Causes an increase in plasma leptin levels and increases food intake in rats in vivo .
storage
Store at +4°C
Properties of SR27897
| Density | 1.49±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at +4°C |
| solubility | DMSO: ≥10mg/mL at warmed to 60°C |
| pka | 4.00±0.10(Predicted) |
| form | powder |
| color | white to tan |
Safety information for SR27897
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for SR27897
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