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HomeProduct name listSR27897

SR27897

SR27897 Structural

What is SR27897?

The Uses of SR27897

SR 27897 is a human cholecystokinin type 1 (CCK1) competitive antagonist.

What are the applications of Application

SR 27897 is an effective non-peptide antagonist of CCK

Definition

ChEBI: 2-[2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]-oxomethyl]-1-indolyl]acetic acid is an indolyl carboxylic acid.

Biological Activity

Potent, non-peptide CCK 1 receptor antagonist that displays > 33-fold selectivity over CCK 2 receptors (EC 50 values are 6 and 200 nM respectively). Causes an increase in plasma leptin levels and increases food intake in rats in vivo .

storage

Store at +4°C

Properties of SR27897

Density  1.49±0.1 g/cm3(Predicted)
storage temp.  Desiccate at +4°C
solubility  DMSO: ≥10mg/mL at warmed to 60°C
pka 4.00±0.10(Predicted)
form  powder
color  white to tan

Safety information for SR27897

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H318:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for SR27897

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