SPIROXATRINE
- CAS NO.：1054-88-2
- Empirical Formula: C22H25N3O3
- Molecular Weight: 379.45
- MDL number: MFCD00055134
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-23 08:32:17
What is SPIROXATRINE?
The Uses of SPIROXATRINE
Spiroxatrine (R 5188) is a SR-1A antagonist.
What are the applications of Application
Spiroxatrine (R 5188) is a SR-1A antagonist
Definition
ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines.
Biological Activity
5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.
Properties of SPIROXATRINE
| Melting point: | 215.8-218.0 °C |
| Boiling point: | 602.8±55.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | 0.1 M HCl: moderately soluble |
| form | powder |
| pka | 15.03±0.20(Predicted) |
| color | white |
Safety information for SPIROXATRINE
Computed Descriptors for SPIROXATRINE
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
![1-[2-(2-METHOXYPHENOXY)ETHYL]-PIPERIDINE](https://img.chemicalbook.in/CAS/GIF/105602-16-2.gif)
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