Solvent Red 27
Synonym(s):1-([4-(Xylylazo)xylyl]azo)-2-naphthol;1-[2,5-Dimethyl-4-(2,5-dimethylphenylazo)phenylazo]-2-naphthol;Solvent Red 27;Sudan Red 5B
- CAS NO.:1320-06-5
- Empirical Formula: C26H24N4O
- Molecular Weight: 408.49
- MDL number: MFCD00003898
- EINECS: 215-295-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is Solvent Red 27?
Physical properties
Solvent Red 27 is a dark green to dark brown crystalline powder.
The Uses of Solvent Red 27
Oil Red O is suitable as a lipid and lipoprotein stain on cellulose acetate. It is one of the diazo dyes used for staining of neutral triglycerides and lipids. It is used to analyze muscle fibers. It acts as an agent that stains lipids, muscle fibers and alveolar macrophages. Further, it is also used as marking dye. It is an active component of red colored smokes in pyrotechnics.
The Uses of Solvent Red 27
Oil Red O has been used for the staining of lipid droplets and lipid-containing vacuoles in cells.
What are the applications of Application
Oil Red O is an agent that stains lipids, muscle fibers and alveolar macrophages
Preparation
2-Amino-2′,3,4′,5-tetramethylazobenzene diazotization, and Naphthalen-2-ol coupling.
Definition
ChEBI: Oil red O is a bis(azo) compound that is 2-naphthol substituted at position 1 by a {4-[(2,5-dimethylphenyl)diazenyl]-2,5-dimethylphenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections and for staining of protein bound lipids in paraffin sections. It has a role as a histological dye. It is a member of azobenzenes, a bis(azo) compound and a member of naphthols. It is functionally related to a 2-naphthol.
General Description
Oil Red O stains lipid materials and imparts red-orange color to the lipids. It also marks vacuoles, particularly observed in ALL-L3 (acute lymphoblastic leukemia) or Burkitt′s lymphoma/leukemia. Oil Red O staining is done on fresh samples, as alcohol fixation removes lipids.
Properties and Applications
blue light red. Soluble in ethanol for yellow red, soluble in acetone, soluble in benzene. In concentrated sulfuric acid to green light blue, blue purple precipitation after dilution.
Standard | Light Fastness | Heat-resistant(℃) | water | Sodium Carbonate(5%) | Hydrochloric acid(5%) | |
Melting point | Stable | |||||
ISO | Well | 108-120 |
70≥ 200
Sublimation |
Insoluble | No change | No change |
Properties of Solvent Red 27
Melting point: | 120 °C (dec.)(lit.) |
Flash point: | 103℃ |
storage temp. | room temp |
solubility | chloroform/ethanol (1:1): soluble1mg/mL |
form | powder |
Colour Index | 26125 |
color | Red to dark greenish-brown |
Water Solubility | Soluble in ethanol:chloroform (1:1). Insoluble in water. |
λmax | 518 nm, 359 nm |
BRN | 3491382 |
Biological Applications | Detecting early stages of atherosclerotic lesion formation; treating obesity,hyperlipidemia,fatty liver,leptin production disorders; dental impression material; measuring phagocytosis |
CAS DataBase Reference | 1320-06-5(CAS DataBase Reference) |
EPA Substance Registry System | C.I. Solvent Red 27 (1320-06-5) |
Safety information for Solvent Red 27
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation H336:Specific target organ toxicity,single exposure; Narcotic effects |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Solvent Red 27
Solvent Red 27 manufacturer
JSK Chemicals
ARRAKIS INDUSTRIES LLP
New Products
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